Tons of stuff in a small space by Jen W. at InsiderPages
Legacy has an extensive collection of comic books. They stock both new and vintage comics. I've spent many hours in the store looking for that perfect comic. They are happy to help you locate comics, even if they are rare. Everyone there is very helpful and some of the guys are even walking comic encyclopedias. The store isn't very large but it is just filled to the brim with great stuff. Plan on spending some time to browse.
Read more at losangeles.citysearch.com
PROS: Tremendous selection
CONS: near downtown Glendale, so parking can be a hassle